Official product information
The label’s own caution first, because on this formula it is the right instruction — then every federal safety statement behind it, quoted rather than paraphrased.
Written and reviewed by the Protoflow Editorial Desk · Last updated September 24, 2026
Quick answer
The label says: “If you are currently taking any medication, consult with a physician prior to use.” On this formula that is the right instruction. Three rows carry published bleeding cautions, the niacin row is more than twice its supplemental upper limit, and seven botanicals have no federal safety page at all.
Start here
Start with the label, because on this formula the label gets it right. Printed on the wrap, in one sentence: “If you are currently taking any medication, consult with a physician prior to use. Do not exceed suggested use.”
One sentence, and on this formula it is the most important sentence on the bottle. Three of the fourteen ingredients — vitamin E, ginkgo and Asian ginseng — carry published warnings about bleeding and anticoagulant medicines. The label tells you to have that conversation. Have it.
That line deserves credit. It names the situation, the action and the timing, and then adds “do not exceed suggested use” — which on a panel carrying a niacin row at 469% of a Daily Value is not a formality.
The rest of this page is what sits behind that sentence: the federal pages, ingredient by ingredient, quoted rather than paraphrased.
Ingredient by ingredient
The only two rows on this panel with published upper limits.
ODS is specific about what happens above 30 mg of nicotinic acid. Supplements at that level and higher can make “the skin on your face, arms, and chest turn red and burn, tingle, and itch. This can also lead to headaches, rashes, and dizziness.”
This serving carries 75 mg, more than twice the adult upper limit. The panel’s 469% is calculated correctly; it is the amount rather than the sum that is the question.
The panel prints “Niacin (Vitamin B3)” and stops. Nicotinic acid flushes at these amounts; niacinamide does not. On a 75 mg row that omission decides how the capsule will feel.
ODS on sustained high-dose use: it “can cause liver problems, including hepatitis and liver failure.” That is the reason a row over a published ceiling is a pharmacist conversation.
This row is small, correct and in the natural d-alpha form, and its 87% of a Daily Value is calculated properly. On its own 13 mg is unremarkable. It carries one published caution, from ODS, and it matters here because of what it is sitting next to.
The stack
Three of the fourteen rows carry the same published warning and they are in the same capsule: vitamin E at 13 mg, ginkgo at 120 mg and Asian ginseng at 120 mg. Here are the three statements, each from the federal page that covers that ingredient.
“Vitamin E can increase the risk of bleeding in people taking anticoagulant or antiplatelet medicines, such as warfarin (Coumadin).”
“Ginkgo may increase the risk of bleeding in people who are taking anticoagulant drugs, such as warfarin.” NCCIH adds that ginkgo “may also interact with other drugs”, and lists its common side effects as “The most common side effects are dizziness, gastrointestinal symptoms, and headache.”
“Asian ginseng may worsen autoimmune disorders and interfere with blood clotting.”
Read a multi-botanical panel for repeats, not just for totals. When three separate rows carry the same caution, the caution is the formula’s, not the ingredient’s. The label’s own line — consult a physician if you take any medication — is the right instruction, and this is the formula that earns it.
This is not a hidden problem: all three are printed with their amounts, which is the only reason anybody can read them as a stack.
What NCCIH publishes
Asian ginseng, hawthorn, saw palmetto and ginkgo.
NCCIH on short-term use: “Short-term oral use (by mouth, up to 6 months) of Asian ginseng in recommended amounts appears to be safe for most people.” That is the reassuring half, and it is worth printing first.
On the most common effect: “Insomnia (trouble sleeping) is the herb’s most common side effect.” That is worth knowing on a product whose front panel calls itself a day and night formula while the directions never split the serving. On blood sugar: “Asian ginseng might lower blood sugar levels.” On the uncommon end: “Uncommon side effects that have been reported include severe rash, liver damage, and severe allergic reactions.” And on conditions: “Asian ginseng may worsen autoimmune disorders and interfere with blood clotting.”
Hawthorn is the joint-largest row on this panel at 250 mg. NCCIH lists possible side effects as “dizziness, nausea, vomiting, diarrhea, and muscle pain.” The more useful statement is about duration: “No research studies have tested whether it is safe to use hawthorn for more than 16 weeks.” Sixteen weeks is about 112 days; the six-bottle pack is 180. Nobody has shown a problem, and nobody has looked.
The friendliest safety entry on the panel. NCCIH: “Saw palmetto is well tolerated.” Adverse effects are reported as mild and infrequent.
One note is worth printing in full, because men taking this ingredient are often the same men having a blood test for it: “Saw palmetto does not appear to affect readings of prostate-specific antigen (PSA) levels, even when taken in higher-than-usual amounts.” That cuts in the product’s favour. For completeness: “Saw palmetto may be unsafe for use during pregnancy or while breastfeeding.”
Ginkgo’s safety statements are in the bleeding section above. Its effectiveness statement belongs here. NCCIH: “There’s no conclusive evidence that ginkgo is helpful for any health condition.”
Epimedium, damiana, muira puama, catuaba, tribulus, oat straw and cayenne have no NCCIH page and no ODS fact sheet, so there is no federal safety statement to print for any of them in either direction.
Condensed
Condensed into the six items worth carrying into a pharmacy.
75 mg per serving against an adult upper limit of 35 mg from supplements. ODS: 30 mg or more of nicotinic acid can make “the skin on your face, arms, and chest turn red and burn, tingle, and itch”, and can lead to “headaches, rashes, and dizziness”. Long-term high-dose use “can cause liver problems, including hepatitis and liver failure”.
Vitamin E, ginkgo and Asian ginseng all carry published anticoagulant cautions. If you take warfarin, an antiplatelet, or anything else that thins the blood, this is a pharmacist conversation before it is a purchase.
NCCIH: it “may worsen autoimmune disorders” and “might lower blood sugar levels”. Insomnia is its most common side effect, which is worth knowing on something called a day and night formula.
NCCIH: “No research studies have tested whether it is safe to use hawthorn for more than 16 weeks.” The six-bottle pack is half a year.
NCCIH: it “may be unsafe for use during pregnancy or while breastfeeding”. This product is sold to adult men, but a bottle in a shared house is a bottle in a shared house.
Epimedium, damiana, muira puama, catuaba, tribulus, oat straw and cayenne have no NCCIH page. That is not a finding of harm. It means nobody has written the plain-language safety summary you would want to read.
Seven silences. The first two matter most here: no allergen statement of any kind, and no statement of which niacin.
There is none. No “contains” line, no “free from” line. Soy is declared where it must be — inside the ingredient list, as soy protein concentrate — but the gluten-free and dairy-free roundels in the marketing pack have nothing on the label behind them.
The panel says “Niacin (Vitamin B3)”. Nicotinic acid flushes at 30 mg and above; niacinamide does not. At 75 mg the distinction matters and the label does not draw it.
Eleven botanical rows and not one ratio, standardisation or marker compound. “Hawthorn (Fruit) 250 mg” could be milled fruit or a concentrated extract, and those are different products.
A distributor is named. The company that made the capsules is not.
No phone, no email, no website on the wrap. Only a street address in Aurora, Colorado.
Not visible on the supplied photograph. Those are normally stamped on the base after filling.
The front says “day & night formula”. The directions say two capsules daily and stop there.
None of these silences is unlawful, and several are ordinary. Listed together, though, they describe how much of this product you are taking on trust.
Before anything else
One more thing on a side-effects page matters more than any statement above, and it is not about the supplement. MedlinePlus on erectile difficulty: “ED can be a sign of health problems. It may mean your blood vessels are clogged. It may mean you have nerve damage from diabetes.” It also notes that ED “becomes more common as you get older. But it’s not a natural part of aging.”
On the symptoms of an enlarged prostate, MedlinePlus is equally direct: “It’s important to see your health care provider if you have any of these symptoms because they could be from a more serious health problem.”
Read those two together and the risk reorders itself. The worst realistic outcome of taking this product is not a flush. It is spending three months on an unstudied botanical capsule while something a doctor could have identified goes unlooked at.
Tell a clinician what you are taking — NCCIH’s own advice is “Take charge of your health—talk with your health care providers about any complementary health approaches you use.” — and take the symptom itself to somebody who can investigate it. No line on this label suggested otherwise: the front-of-bottle claims name no condition and no hormone.
Questions
Vitamin E, ginkgo and Asian ginseng. ODS on vitamin E: it “can increase the risk of bleeding in people taking anticoagulant or antiplatelet medicines, such as warfarin (Coumadin)”. NCCIH on ginkgo: it “may increase the risk of bleeding in people who are taking anticoagulant drugs”. NCCIH on Asian ginseng: it “may worsen autoimmune disorders and interfere with blood clotting”.
It is the row to ask about. 75 mg is more than twice the 35 mg adult upper limit for niacin from supplements. ODS reports that 30 mg or more of nicotinic acid can make “the skin on your face, arms, and chest turn red and burn, tingle, and itch”, and that long-term high-dose use “can cause liver problems, including hepatitis and liver failure”. The label does not say which form it uses.
No, and MedlinePlus makes the reason concrete rather than abstract: “ED can be a sign of health problems. It may mean your blood vessels are clogged. It may mean you have nerve damage from diabetes.” On urinary symptoms it is equally plain that they “could be from a more serious health problem”.
References
Next
Five exclusions, starting with the one the ingredient list decides.
Read it →Every row against the federal page that covers it.
Read it →The facts table, the caution and the storage line.
Read it →Sixty capsules a bottle, two capsules daily with water, thirty days a bottle. Fourteen ingredients, fourteen published amounts, no proprietary blend. The capsule shell is gelatin. No pack price was supplied to this desk, so read the figure on the sales page before you pay. Sixty days from purchase to change your mind. The order desk supplied to us is +1 (302) 200-3480.
Price shown at checkout · 60-day window from the date of purchase · ships from inside the US · the label’s own support line is +1 (302) 200-3480